Clinical specimen: Sputum/BAL/Tissue/Urine/Body fluid
TEST DESCRIPTION:
1. This test is based on targeted next generation sequencing.
2. This test covered all 15 genes (RPOB, EIS, EMBB, ETHA, KATG, INHA, GID, GYRA, GYRB, RPLC, RPSL, RRS, RV0678, TLYA, PNCA) recommended by WHO for drug resistance in Mycobacterium tuberculosis (https://www.who.int/publications/i/item/9789240082410).
3. Targeted drugs:
First line drugs:
Rifampicin (RIF), Isoniazid (INH), Pyrazinamide (PZA), Ethambutol (EMB)
Second line injectables:
Streptomycin (SM), Kanamycin (KAN), Amikacin (AMI), Capreomycin (CAP)
Fluoroquinolone class (FQ):
Levofloxacin (LEV), Moxifloxacin (MOX), Ethionamide (ETH), Linezolid (LIN), Bedaquiline (BDQ), Clofazimine (CFZ)